Population structure of Plasmodium falciparum gametocyte sex ratios in malarious children in an endemic area

Plasmodium falciparum gametocyte carriage, emergence, clearance and population sex ratios in anaemic and non-anaemic malarious children.

Anaemia in falciparum malaria is associated with an increased risk of gametocyte carriage, but its effects on transmission have not been extensively evaluated in malarious children. Plasmodium falciparum gametocyte carriage, emergence, clearance, population sex ratios (SR) (defined as the proportion of gametocytes that are male), inbreeding rates and temporal changes in SR were evaluated in 840...

Influence of Anemia on Plasmodium falciparum Gametocyte Sex Ratios in Acutely Symptomatic Children

Anemia is common in African children but little is known about how malarial anemia influences Plasmodium falciparum gametocyte sex ratios (PfGSR) and transmission in endemic areas in Africa. We investigated the changes in PfGSR in 1126 consecutive children with acute, symptomatic, uncomplicated falciparum malaria who did (n = 99) or did not (n = 1027) have anemia (defined as a hematocrit < 25%)...

Risk factors for Plasmodium falciparum hyperparasitaemia in malarious children

BACKGROUND Hyperparasitaemia is a feature of childhood severe malaria but there is little information on the risk factors for hyperparasitaemia in malarious children METHODS The risk factors associated with Plasmodium falciparum hyperparasitaemia, defined as asexual parasitaemia > 250,000/μl, at presentation were evaluated in 3338 malarious children enrolled prospectively between 2008 and 201...

Gametocyte and gamete development in Plasmodium falciparum.

Plasmodium falciparum gametocytaemia with chloroquine chemotherapy in persistent malaria in an endemic area of India.

BACKGROUND & OBJECTIVE Gametocyte sex-ratio in Plasmodium falciparum malaria is an important determinant of transmission success and basis of disease epidemiology. Information on ratio of male to female gametocytes after an exposure of antimalarial regimens under field conditions is very limited. In this retrospective study we observed high densities of gametocytes along with high sex-ratio in ...